Acute pain, regardless of the degree, resolves when tissues heal and is usually a short-term problem. Chronic pain, which is a disease state in itself, may persist for months or years. Acute pain usually involves brief nociceptive input to the central nervous system (CNS), but chronic pain is primarily the result of a neuropathic injury or modulation within the CNS.
Discomfort is ameliorated by a variety of medications, among which are opioids, nonsteroidal anti-inflammatory drugs (NSAIDs), and steroids. Chronic discomfort can be caused by malignant or non-malignant diseases. Chronic or acute discomfort that results from a malignant condition is usually relieved by opioid therapy; however, some patients become opioid tolerant. Opioids often do ... View More