Topical Ketamine 10% for Neuropathic Pain

Topical Ketamine 10% for Neuropathic Pain in Spinal Cord Injury Patients Ketamine is a NMDA antagonist.  Therefore, topical Ketamine can be effective in certain neuropathic pain syndromes.  An open label trial enrolled five subjects at an outpatient rehabilitation hospital with traumatic spinal cord injuries who had neuropathic pain at or below the level of injury.  Subjects applied Ketamine 10% for Neuropathic Pain three times a day for a two-week duration.  All five subject had a decrease in their pain scale by the end of two weeks!  The pain relief lasted anywhere from one hour in one subject to the next application in other subjects.

No adverse effects were seen in topical ketamine 10% for neuropathic pain.  Overall, four out of the five subjects stated that they were satisfied ... View More

TMJ Disorder- The Painful (but Helpful) Truth

Temporomandibular joint (TMJ) disorder refers to a cluster of conditions characterized by pain in the TMJ or its surrounding tissues.1 TMJ conditions are common in the adult population and up to 75 percent of adults show at least one sign of joint dysfunction on examination and as many as one third have at least one symptom.2,3

The TMJ is a synovial joint that contains an articular disk, which allows for hinge and sliding movements.  This complex combination of movements allows for painless and efficient chewing, swallowing, and speaking. There is some evidence to suggest that anxiety, stress, and other emotional disturbances may exacerbate TMJ disorders. Common symptoms of TMJ disorders include jaw pain, limited or painful jaw movements, headache, neck pain or stiffness, clicking ... View More